The Netsphere refers to the hyper-evolved version of the Internet in the universe of BLAME!. Ancient humans could interact with the Netsphere using a specific gene called the Net Terminal Gene and create anything they imagined in the real world from a digital template. Since the Netsphere essentially granted wishes to those who could access it, Net Terminal Gene carriers were likened to gods over the rest of humanity, who could not access the Netsphere.